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Santorini can be reached by plane from all over the word.You can find all direct or indirect flights here.
Santorini Airport is besides Messasria, 4 klm far from Fira and 10 from Oia.
rent-a-Car companies, and taxis are there.
Santorini Island is in the middle of the Aegean Sea(between the mainland and Crete). It's worth to travel by boat to Santorini. The view of the island from the sea level is astonishing. A real life's experience. You will need 8-10 h on a normal boat from Piraeus port and the falf of the time on a High-Speed boat. All boat trips schedule can be found here. 
Santorini is accessed by boats from major ports.
Small boats round trips take place several times a day.

Santorini weather: 
http://www.meteo.gr/cf.asp?city_id=20

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